I personally do not notice a huge difference between the levels of play. I play regularly at NL25, NL50, and NL100 tables, and my basic strategy remains the same: Bluff sparingly, protect big hands, and most importantly don't force yourself to play hands that you should not play.
I usually don't take many risks while playing cash games. My reason for this is simple: There is an enormous amount of stupid, reckless play on PartyPoker; it occurs at all stakes, not just at NL25. Therefore, it is often the best strategy to simply sit back and wait for the cards to come, and then take advantage of your loose opponent. Granted, not all players on PartyPoker are stupid and reckless, but it's not very difficult to find players who are.
I know that sitting back and waiting for the cards to come is not the most profitable method of playing poker, but for the purpose of playing on Party, it works just fine.
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