I usually donk bet strong - flopped set, for example - and/or when I can squeeze a guy behind me. If the PFR is the one in between me and another cold caller, I definitely wouldn't donk bet (because I don't want him to raise and drive the other player out), but if the preflop raiser was the last to act, that's a good spot to squeeze the guy in the middle if you have a big hand. So, it really depends.
Generally though, I don't donk bet much. Heads Up, I'd prefer to check raise or check/call, depending how strong my hand is (or check/fold, of course). But on some flops against the right type of opponent, the donk bet will work too.
Sorry if this isn't a good explanation, but it's very situation dependent.
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