Very flop and opponent dependent
2 examples follow
- Try not to CB against more than 2 opponents that often, unless it's A super dry board/a board that isnt likely to have hit anyone i.e 6

2

2
- You raise 2nd position with 66 and the CO and button call. The flop comes T

J

Q

. It's just too likely that you are either beat, or opponents will call on some sort of draw... and you are OOP so you are put to a tough decision on the turn (double barrelling a large bet if you put opponent on a draw or shutting down and perhaps letting a draw steal)