Ok, I haven't read this entire post, but I remember reading a story in I believe Hellmuth's book about Negreanu playing these all the time when there are many people in before the flop and he is in late position. I really wouldn't be comfortable playing anything less than 45 suited myself though, since you are then drawing to a straight at both ends IE 32A or 678. If you play 34, then A2 helps but then you have a gutshot needing the 5.
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That's how I rolled.
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